• ISSN 1674-8301
  • CN 32-1810/R
Volume 25 Issue 6
Nov.  2011
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Tongfu Yu, Mei Yuan, Qingbo Zhang, Haibing Shi, Dehang Wang. Evaluation of computed tomography obstruction index in guiding therapeutic decisions and monitoring percutanous catheter fragmentation in massive pulmonary embolism[J]. The Journal of Biomedical Research, 2011, 25(6): 431-437. doi: 10.1016/S1674-8301(11)60057-2
Citation: Tongfu Yu, Mei Yuan, Qingbo Zhang, Haibing Shi, Dehang Wang. Evaluation of computed tomography obstruction index in guiding therapeutic decisions and monitoring percutanous catheter fragmentation in massive pulmonary embolism[J]. The Journal of Biomedical Research, 2011, 25(6): 431-437. doi: 10.1016/S1674-8301(11)60057-2

Evaluation of computed tomography obstruction index in guiding therapeutic decisions and monitoring percutanous catheter fragmentation in massive pulmonary embolism

doi: 10.1016/S1674-8301(11)60057-2
  • Received Date: 2011-04-20
  • In the present study, we evaluated computed tomography pulmonary angiography (CTPA) in guiding therapeu-tic decisions and monitoring patients undergoing percutaneous catheter fragmentation in acute massive pulmonary embolism. From Jan 2003 to Dec 2009, 35 patients were diagnosed with acute massive pulmonary embolism by CTPA (T0) and treated with percutaneous catheter fragmentation. The severity was assessed by CT obstruction index (Qanadli index) and compared with Miller index. CTPA, oxygen saturation (SaO2) and pulmonary artery pressure were performed as follow-up index. The mean percentage of Qanadli index was (55±13)% (range, 40%-75%), and Miller index was (62±15)% (range, 45%–85%). Correlations between them were statistically signifi-cant (r = 0.867, P < 0.0001). The Qanadli index showed significant reduction [T0: (55±13)%; T1: (12±10)%; P < 0.001] in 33 patients. Significant correlation was observed between the Qanadli index, SaO2 (r = 0.934), and pulmonary artery pressure (r = 0.813). The Qanadli index provides an accurate method for distinguishing massive pulmonary embolism from sub-massive pulmonary embolism. It can be used to determine therapeutic options and monitor clinical outcomes.
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通讯作者: 陈斌, bchen63@163.com
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Evaluation of computed tomography obstruction index in guiding therapeutic decisions and monitoring percutanous catheter fragmentation in massive pulmonary embolism

doi: 10.1016/S1674-8301(11)60057-2

Abstract: In the present study, we evaluated computed tomography pulmonary angiography (CTPA) in guiding therapeu-tic decisions and monitoring patients undergoing percutaneous catheter fragmentation in acute massive pulmonary embolism. From Jan 2003 to Dec 2009, 35 patients were diagnosed with acute massive pulmonary embolism by CTPA (T0) and treated with percutaneous catheter fragmentation. The severity was assessed by CT obstruction index (Qanadli index) and compared with Miller index. CTPA, oxygen saturation (SaO2) and pulmonary artery pressure were performed as follow-up index. The mean percentage of Qanadli index was (55±13)% (range, 40%-75%), and Miller index was (62±15)% (range, 45%–85%). Correlations between them were statistically signifi-cant (r = 0.867, P < 0.0001). The Qanadli index showed significant reduction [T0: (55±13)%; T1: (12±10)%; P < 0.001] in 33 patients. Significant correlation was observed between the Qanadli index, SaO2 (r = 0.934), and pulmonary artery pressure (r = 0.813). The Qanadli index provides an accurate method for distinguishing massive pulmonary embolism from sub-massive pulmonary embolism. It can be used to determine therapeutic options and monitor clinical outcomes.

Tongfu Yu, Mei Yuan, Qingbo Zhang, Haibing Shi, Dehang Wang. Evaluation of computed tomography obstruction index in guiding therapeutic decisions and monitoring percutanous catheter fragmentation in massive pulmonary embolism[J]. The Journal of Biomedical Research, 2011, 25(6): 431-437. doi: 10.1016/S1674-8301(11)60057-2
Citation: Tongfu Yu, Mei Yuan, Qingbo Zhang, Haibing Shi, Dehang Wang. Evaluation of computed tomography obstruction index in guiding therapeutic decisions and monitoring percutanous catheter fragmentation in massive pulmonary embolism[J]. The Journal of Biomedical Research, 2011, 25(6): 431-437. doi: 10.1016/S1674-8301(11)60057-2

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