CiteULike  View Full Text   View/Add Comment  Download reader    
Chen Liang,Ling Yang,Shiwen Guo.Journal of Biomedical Research,2018,32(4):305-310
Serial lumbar puncture reduces cerebrospinal fluid (CSF) infection during removal of hemorrhagic CSF in aneurysmal subarachnoid hemorrhage after endovascular coiling
Received:March 16, 2017  Revised:December 12, 2017
DOI£º10.7555/JBR.32.20170028
Keywords£ºserial lumbar puncture, cerebrospinal fluid infection, aneurysmal subarachnoid hemorrhage
Grant Program£º
¡¡¡¡ ¡¡¡¡ ¡¡¡¡
AuthorInstitution
Chen Liang Department of Neurosurgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi , China
Ling Yang Department of Aeromedical Physical Examination, Xi'an Civil Aviation Hospital, Xi'an, Shaanxi , China
Shiwen Guo Department of Neurosurgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi , China
Hits: 245
Download times: 41
      
Abstract £º
      The present study aimed to compare the complications and clinical outcomes of serial lumbar puncture (LP) and lumbar cerebrospinal fluid (CSF) drainage (LD) of patients with aneurysmal subarachnoid hemorrhage and provide more evidence to guide clinical management. In this retrospective study, 41 and 39 aneurysmal subarachnoid hemorrhage patients were enrolled in the LP and LD group, respectively. Clinical outcomes, including CSF infection, intracerebral hemorrhage, vasospasm, hydrocephalus, death, length of stay, duration of drainage and the Glasgow Outcome Scale score were compared between the two groups. By comparing with the LP group, the LD group showed a significantly higher rate of CSF infection (P = 0.029) and shorter duration of drainage (P < 0.001). Both groups displayed similar rates of vasospasm, hydrocephalus, intracerebral hemorrhage, the Glasgow Outcome Scale score one month after endovascular coiling and length of stay (P > 0.05, respectively). In conclusion, both LD and serial LP are effective methods in the treatment of aneurysmal subarachnoid hemorrhage; besides, serial LP can reduce the incidence of CSF infection in draining hemorrhagic CSF in aneurysmal subarachnoid hemorrhage after endovascular coiling.
Close