• ISSN 1674-8301
  • CN 32-1810/R
Volume 37 Issue 2
Mar.  2023
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Article Contents
Xiangqin Xu, Jiansheng Zhu, May Lei Mei, Huaying Wu, Kaipeng Xie, Shoulin Wang, Yaming Chen. Exploration and preliminary clinical investigation of an adhesive approach for primary tooth restoration[J]. The Journal of Biomedical Research, 2023, 37(2): 138-147. doi: 10.7555/JBR.36.20220188
Citation: Xiangqin Xu, Jiansheng Zhu, May Lei Mei, Huaying Wu, Kaipeng Xie, Shoulin Wang, Yaming Chen. Exploration and preliminary clinical investigation of an adhesive approach for primary tooth restoration[J]. The Journal of Biomedical Research, 2023, 37(2): 138-147. doi: 10.7555/JBR.36.20220188

Exploration and preliminary clinical investigation of an adhesive approach for primary tooth restoration

doi: 10.7555/JBR.36.20220188
Funds:  This work was supported by the Technology Development Fund of Nanjing Medical University [Grants No. NMUB2016115 and NMUB2020117].
More Information
  • Corresponding author: Shoulin Wang, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Nanjing, Jiangsu 211166, China. E-mail: wangshl@njmu.edu.cn; Yaming Chen, Comprehensive Outpatient Department of Stomatology, the Affiliated Hospital of Stomatology of Nanjing Medical University, 136 Hanzhong Road, Nanjing, Jiangsu 210029, China. Tel/Fax: +86-25-6969-3022, E-mail: yaming_chen@njmu.edu.cn
  • Received: 2022-08-24
  • Revised: 2022-10-18
  • Accepted: 2022-10-27
  • Published: 2022-11-28
  • Issue Date: 2023-03-28
  • The current study aims to investigate a suitable adhesive for primary tooth enamel. Shear bond strength (SBS) of primary teeth and the length of resin protrusion were analyzed using one-way ANOVA with Bonferroni multiple comparison tests after etching with 35% H3PO4. SBS and marginal microleakage tests were conducted with Single Bond Universal (SBU)/Single Bond 2 (SB2) adhesives with or without pre-etching using a nonparametric Kruskal-Wallis test. Clinical investigations were performed to validate the adhesive for primary teeth restoration using Chi-square tests. Results showed that the SBS and length of resin protrusion increased significantly with the etching time. Teeth in the SBU with 35% H3PO4 pre-etching groups had higher bond strength and lower marginal microleakage than those in the SB2 groups. Mixed fractures were more common in the 35% H3PO4 etched 30 s + SB2/SBU groups. Clinical investigations showed significant differences between the two groups in cumulative retention rates at the 6-, 12- and 18-month follow-up evaluations, as well as in marginal adaptation, discoloration, and secondary caries at the 12- and 18-month follow-up assessments. Together, pre-etching primary teeth enamel for 30 s before SBU treatment improved clinical composite resin restoration, which can provide a suitable approach for restoration of primary teeth.

     

  • CLC number: R783.1, Document code: A
    The authors reported no conflict of interests.
    △These authors contributed equally to this work.
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