[1] Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics-2014 update: a report from the American Heart Association[J]. Circulation, 2014, 129(3): e28–e292.
[2] Boengler K, Schulz R, Heusch G. Loss of cardioprotection with ageing[J]. Cardiovasc Res, 2009, 83(2): 247–261. doi:  10.1093/cvr/cvp033
[3] Hariharan N, Sussman MA. Cardiac aging- Getting to the stem of the problem[J]. J Mol Cell Cardiol, 2015, 83: 32–36. doi:  10.1016/j.yjmcc.2015.04.008
[4] Liu X, Lei J, Wang K, et al. Mitochondrial Omi/HtrA2 promotes caspase activation through cleavage of HAX-1 in aging heart[J]. Rejuvenation Res, 2017, 20(3): 183–192. doi:  10.1089/rej.2016.1861
[5] Bıçakçı H, Sarsılmaz M, Ocaklı S, et al. Investigation of the effects of aging on the expression of aquaporin 1 and aquaporin 4 protein in heart tissue[J]. Anatol J Cardiol, 2017, 17(1): 18–23.
[6] Lesnefsky EJ, Gudz TI, Moghaddas S, et al. Aging decreases electron transport complex Ⅲ activity in heart interfibrillar mitochondria by alteration of the cytochrome c binding site[J]. J Mol Cell Cardiol, 2001, 33(1): 37–47. doi:  10.1006/jmcc.2000.1273
[7] Villmow M, Klöckner U, Heymes C, et al. NOS1 induces NADPH oxidases and impairs contraction kinetics in aged murine ventricular myocytes[J]. Basic Res Cardiol, 2015, 110(5): 506.
[8] Ma L, Zhu J, Gao Q, et al. Restoring pharmacologic preconditioning in the aging heart: role of mitophagy/autophagy[J]. J Gerontol A Biol Sci Med Sci, 2017, 72(4): 489–498.
[9] Kersten JR, Schmeling TJ, Pagel PS, et al. Isoflurane mimics ischemic preconditioning via activation of K(ATP) channels: reduction of myocardial infarct size with an acute memory phase[J]. Anesthesiology, 1997, 87(2): 361–370. doi:  10.1097/00000542-199708000-00024
[10] Konia MR, Schaefer S, Liu H. NF-Kappa B inhibition provides additional protection ischemia-reperfusion injury in delayed sevoflurane preconditioning[J]. Eur J Anaesthesiol, 2009, 26(6): 496–503 P. doi:  10.1097/EJA.0b013e328324ed2e
[11] Xuan YT, Tang XL, Banerjee S, et al. Nuclear factor-kappaB plays an essential role in the late phase of ischemic preconditioning in conscious rabbits[J]. Circ Res, 1999, 84(9): 1095–1109. doi:  10.1161/01.RES.84.9.1095
[12] Zhong C, Zhou Y, Liu H. Nuclear factor kappaB and anesthetic preconditioning during myocardial ischemia-reperfusion[J]. Anesthesiology, 2004, 100(3): 540–546. doi:  10.1097/00000542-200403000-00012
[13] Wang C, Xie H, Liu X, et al. Role of NF-κB in volatile anesthetic preconditioning with sevoflurane during myocardial ischemia/reperfusion in rats[J]. Eur J Anaesthesiol, 2010, 27(8): 747–756.
[14] Lutz M, Liu H. Inhaled sevoflurane produces better delayed myocardial protection at 48 versus 24 hours after exposure[J]. Anesth Analg, 2006, 102(4): 984–990. doi:  10.1213/01.ane.0000198568.79079.4c
[15] Deyhimy DI, Fleming NW, Brodkin IG, et al. Anesthetic preconditioning combined with postconditioning offers no additional benefit over preconditioning or postconditioning alone[J]. Anesth Analg, 2007, 105(2): 316–324. doi:  10.1213/01.ane.0000267524.71445.e7
[16] Sniecinski R, Liu H. Reduced efficacy of volatile anesthetic preconditioning with advanced age in isolated rat myocardium[J]. Anesthesiology, 2004, 100(3): 589–597. doi:  10.1097/00000542-200403000-00019
[17] Nguyen LT, Rebecchi MJ, Moore LC, et al. Attenuation of isoflurane-induced preconditioning and reactive oxygen species production in the senescent rat heart[J]. Anesth Analg, 2008, 107(3): 776–782. doi:  10.1213/ane.0b013e318180419d
[18] Winker MA. Aging in the 21st century: a call for papers[J]. Arch Neurol, 2002, 59(4): 518–519. doi:  10.1001/archneur.59.4.518
[19] Swynghedauw B, Besse S, Assayag P, et al. Molecular and cellular biology of the senescent hypertrophied and failing heart[J]. Am J Cardiol, 1995, 76(13): 2D–7D. doi:  10.1016/S0002-9149(99)80484-6
[20] Chang WT, Chen JS, Tsai MH, et al. Interplay of aging and hypertension in cardiac remodeling: a mathematical geometric model[J]. PLoS One, 2016, 11(12): e0168071. doi:  10.1371/journal.pone.0168071
[21] Liu H, Wang L, Eaton M, et al. Sevoflurane preconditioning limits intracellular/mitochondrial Ca2+ in ischemic newborn myocardium[J]. Anesth Analg, 2005, 101(2): 349–355. doi:  10.1213/01.ANE.0000154197.24763.EC
[22] Liu H, Moore PGK. KATP channel blocker does not abolish the protective effect of Na+/H+ exchange 1 inhibition against ischaemia/reperfusion in aged myocardium[J]. Eur J Anaesthesiol, 2010, 27(8): 740–746.
[23] Xie H, Wang C, Wu X, et al. Parthenolide attenuates LPSinduced activation of NF-κB in a time-dependent manner in rat myocardium[J]. J Biomed Res, 2012, 26(1): 37–43. doi:  10.1016/S1674-8301(12)60005-0
[24] Choi H, Kim SH, Chun YS, et al. In vivo hyperoxic preconditioning prevents myocardial infarction by expressing bcl-2[J]. Exp Biol Med (Maywood), 2006, 231(4): 463–472. doi:  10.1177/153537020623100412
[25] Grünenfelder J, Miniati DN, Murata S, et al. Upregulation of Bcl-2 through caspase-3 inhibition ameliorates ischemia/reperfusion injury in rat cardiac allografts[J]. Circulation, 2001, 104(12 Suppl 1): I202–I206.