[1] Maione F, De Feo V, Caiazzo E, et al. Tanshinone IIA, a major component of Salvia milthorriza Bunge, inhibits platelet activation via Erk-2 signaling pathway[J]. J Ethnopharmacol, 2014, 155(2): 1236–1242. doi:  10.1016/j.jep.2014.07.010
[2] Michel JB, Martin-Ventura JL, Nicoletti A, et al. Pathology of human plaque vulnerability: mechanisms and consequences of intraplaque haemorrhages[J]. Atherosclerosis, 2014, 234(2): 311–319. doi:  10.1016/j.atherosclerosis.2014.03.020
[3] Barrett NE, Holbrook L, Jones S, et al. Future innovations in antiplatelet therapies[J]. Br J Pharmacol, 2008, 154(5): 918–939. doi:  10.1038/bjp.2008.151
[4] Rastogi S, Pandey MM, Rawat AK. Traditional herbs: a remedy for cardiovascular disorders[J]. Phytomedicine, 2016, 23(11): 1082–1089. doi:  10.1016/j.phymed.2015.10.012
[5] Kerver JM, Yang EJ, Bianchi L, et al. Dietary patterns associated with risk factors for cardiovascular disease in healthy US adults[J]. Am J Clin Nutr, 2003, 78(6): 1103–1110. doi:  10.1093/ajcn/78.6.1103
[6] Dutta-Roy AK. Dietary components and human platelet activity[J]. Platelets, 2002, 13(2): 67–75. doi:  10.1080/09537100120111540
[7] Byun MW. Schizonepeta tenuifolia ethanol extract exerts antiinflammatory activity through the inhibition of TLR4 signaling in lipopolysaccharide-stimulated macrophage cells[J]. J Med Food, 2014, 17(3): 350–356. doi:  10.1089/jmf.2013.2928
[8] Kim SJ, Kim JS, Choi IY, et al. Anti-inflammatory activity of Schizonepeta tenuifolia through the inhibition of MAPK phosphorylation in mouse peritoneal macrophages[J]. Am J Chin Med, 2008, 36(6): 1145–1158. doi:  10.1142/S0192415X0800648X
[9] Wang BS, Huang GJ, Tai HM, et al. Antioxidant and antiinflammatory activities of aqueous extracts of Schizonepeta tenuifolia Briq[J]. Food Chem Toxicol, 2012, 50(3–4): 526–531. doi:  10.1016/j.fct.2011.12.010
[10] Shin TY, Jeong HJ, Jun SM, et al. Effect of Schizonepeta tenuifolia extract on mast cell-mediated immediate-type hypersensitivity in rats[J]. Immunopharmacol Immunotoxicol, 1999, 21(4): 705–715. doi:  10.3109/08923979909007136
[11] Kang H, Oh YJ, Choi HY, et al. Immunomodulatory effect of Schizonepeta tenuifolia water extract on mouse Th1/Th2 cytokine production in-vivo and in-vitro[J]. J Pharm Pharmacol, 2008, 60(7): 901–907. doi:  10.1211/jpp.60.7.0012
[12] Tohda C, Kakihara Y, Komatsu K, et al. Inhibitory effects of methanol extracts of herbal medicines on substance P-induced itch-scratch response[J]. Biol Pharm Bull, 2000, 23(5): 599–601. doi:  10.1248/bpb.23.599
[13] Endale M, Lee WM, Kamruzzaman SM, et al. Ginsenoside-Rp1 inhibits platelet activation and thrombus formation via impaired glycoprotein VI signalling pathway, tyrosine phosphorylation and MAPK activation[J]. Br J Pharmacol, 2012, 167(1): 109–127. doi:  10.1111/j.1476-5381.2012.01967.x
[14] Kamruzzaman SM, Endale M, Oh WJ, et al. Inhibitory effects of Bulnesia sarmienti aqueous extract on agonist-induced platelet activation and thrombus formation involves mitogenactivated protein kinases[J]. J Ethnopharmacol, 2010, 130(3): 614–620. doi:  10.1016/j.jep.2010.05.049
[15] Schaeffer J, Blaustein MP. Platelet free calcium concentrations measured with fura-2 are influenced by the transmembrane sodium gradient[J]. Cell Calcium, 1989, 10(2): 101–113. doi:  10.1016/0143-4160(89)90050-X
[16] Schlossmann J, Ammendola A, Ashman K, et al. Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta[J]. Nature, 2000, 404(6774): 197–201. doi:  10.1038/35004606
[17] Ren Q, Wimmer C, Chicka MC, et al. Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis[J]. Blood, 2010, 116(6): 869–877. doi:  10.1182/blood-2010-02-270934
[18] Calderwood DA. Integrin activation[J]. J Cell Sci, 2004, 117(Pt 5): 657–666.
[19] Adam F, Kauskot A, Rosa JP, et al. Mitogen-activated protein kinases in hemostasis and thrombosis[J]. J Thromb Haemost, 2008, 6(12): 2007–2016. doi:  10.1111/jth.2008.6.issue-12
[20] Park KM, Kramers C, Vayssier-Taussat M, et al. Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction[J]. J Biol Chem, 2002, 277(3): 2040–2049. doi:  10.1074/jbc.M107525200
[21] Chuang WY, Kung PH, Kuo CY, et al. Sulforaphane prevents human platelet aggregation through inhibiting the phosphatidylinositol 3-kinase/Akt pathway[J]. Thromb Haemost, 2013, 109(6): 1120–1130. doi:  10.1160/TH12-09-0636
[22] Gibbins JM. Platelet adhesion signalling and the regulation of thrombus formation[J]. J Cell Sci, 2004, 117(Pt16): 3415–3425.
[23] Park JY, Ji HD, Jeon BR, et al. Chlorin e6 prevents ADPinduced platelet aggregation by decreasing PI3K-Akt phosphorylation and promoting cAMP production[J]. Evid Based Complement Alternat Med, 2013, 2013: 569160.
[24] Shan MQ, Qian Y, Yu S, et al. Anti-inflammatory effect of volatile oil from Schizonepeta tenuifolia on carrageenininduced pleurisy in rats and its application to study of appropriate harvesting time coupled with multi-attribute comprehensive index method[J]. J Ethnopharmacol, 2016, 194: 580–586. doi:  10.1016/j.jep.2016.10.045
[25] Sancheti S, Sancheti S, Lee SH, et al. Screening of Korean medicinal plant extracts for α-glucosidase inhibitory activities[J]. Iran J Pharm Res, 2011, 10(2): 261–264.
[26] Berridge MJ, Bootman MD, Roderick HL. Calcium signalling: dynamics, homeostasis and remodelling[J]. Nat Rev Mol Cell Biol, 2003, 4(7): 517–529.
[27] Ruggeri ZM. Platelets in atherothrombosis[J]. Nat Med, 2002, 8(11): 1227–1234. doi:  10.1038/nm1102-1227
[28] Phillips DR, Prasad KS, Manganello J, et al. Integrin tyrosine phosphorylation in platelet signaling[J]. Curr Opin Cell Biol, 2001, 13(5): 546–554. doi:  10.1016/S0955-0674(00)00250-7
[29] Ruggeri ZM, Mendolicchio GL. Adhesion mechanisms in platelet function[J]. Circ Res, 2007, 100(12): 1673–1685. doi:  10.1161/01.RES.0000267878.97021.ab
[30] Kuliopulos A, Mohanlal R, Covic L. Effect of selective inhibition of the p38 MAP kinase pathway on platelet aggregation[J]. Thromb Haemost, 2004, 92(6): 1387–1393.
[31] Wu H, Ye M, Yang J, et al. Nicorandil protects the heart from ischemia/reperfusion injury by attenuating endoplasmic reticulum response-induced apoptosis through PI3K/Akt signaling pathway[J]. Cell Physiol Biochem, 2015, 35(6): 2320–2332. doi:  10.1159/000374035
[32] Chun MH, Kim EK, Lee KR, et al. Quality control of Schizonepeta tenuifolia Briq by solid-phase microextraction gas chromatography/mass spectrometry and principal component analysis[J]. Microchem J, 2010, 95: 25–31. doi:  10.1016/j.microc.2009.09.009