• Journal of Biomedical Research is a peer reviewed open access journal dedicated to publishing high-quality research in all areas of the biological and medical sciences.
Current Issue             Journal of Biomedical Research--2018, 32(3)
Cognitive function assessment should be included in preoperative evaluation
David Li,Hong Liu

J Biomed Res 2018;32(3):161-163.   doi:10.7555/JBR.32.20180008
The pleiotropic vasoprotective functions of high density lipoproteins (HDL)
Guilaine Boyce,Emily Button,Sonja Soo,Cheryl Wellington,
The pleiotropic functions of circulating high density lipoprotein (HDL) on peripheral vascular health are well established. HDL plays a pivotal role in reverse cholesterol transport and is also known to suppress inflammation, endothelial activation and apoptosis in peripheral vessels. Although not e...more>>
J Biomed Res 2018;32(3):164-182.   doi:10.7555/JBR.31.20160103
Apolipoprotein E in diet-induced obesity: a paradigm shift from conventional perception
Kyriakos E. Kypreos,Eleni A. Karavia,Caterina Constantinou,Aikaterini Hatziri,Christina Kalogeropoulou,Eva Xepapadaki,Evangelia Zvintzou
Apolipoprotein E (APOE) is a major protein component of peripheral and brain lipoprotein transport systems. APOE in peripheral circulation does not cross the blood brain barrier or blood cerebrospinal fluid barrier. As a result, peripheral APOE expression does not affect brain APOE levels and vice v...more>>
J Biomed Res 2018;32(3):183-190.   doi:10.7555/JBR.32.20180007
Effect of neoadjuvant chemotherapy on the expression of hormone receptors and Ki67 in Chinese breast cancer patients: A retrospective study of 525 patients
Yu-tuan Wu,Xin Li,Lin-jie Lu,Lu Gan,Wei Dai,Yan-ling Shi,Vishnu Prasad Adhikari,Kai-nan Wu,Ling-quan Kong
This study was designed to investigate the effect of neoadjuvant chemotherapy on the expression of hormone receptors and Ki67 in Chinese female breast cancer patients. The expression of estrogen receptor (ER), progesterone receptor (PR) and Ki67 among 525 neoadjuvant chemotherapy cases was studied b...more>>
J Biomed Res 2018;32(3):191-197.   doi:10.7555/JBR.32.20170059
Diagnostic performance of contrast-enhanced ultrasound and enhanced magnetic resonance for breast nodules
Cuiying Li,Haiyan Gong,Lijun Ling,Liwen Du,Tong Su,Shui Wang,Jie Wang
In the current study, we sought to evaluate the diagnostic efficacies of conventional ultrasound (US), contrastenhanced US (CEUS), combined US and CEUS and magnetic resonance imaging (MRI) in detecting focal solid breast lesions. Totally 117 patients with 120 BI-RADS category 4A-5 breast lesions wer...more>>
J Biomed Res 2018;32(3):198-207.   doi:10.7555/JBR.32.20180015
Follicular hyperandrogenism and insulin resistance in polycystic ovary syndrome patients with normal circulating testosterone levels
Andi Li,Lu Zhang,Jiajia Jiang,Nan Yang,Ying Liu,Lingbo Cai,Yugui Cui,Feiyang Diao,Xiao Han,Jiayin Liu,Yujie Sun
Polycystic ovary syndrome (PCOS) is a common reproductive disease with high heterogeneity. The role of excess androgen in PCOS etiology remains disputed, since around 20%–50% of PCOS women do not display hyperandrogenemia. The microenvironment of the ovary critically influences follicular developmen...more>>
J Biomed Res 2018;32(3):208-214.   doi:10.7555/JBR.32.20170136
Tcf7l1 promotes transcription of Kruppel-like factor 4 during Xenopus embryogenesis
Qing Cao,Yan Shen,Wei Zheng,Hao Liu,Chen Liu
Kruppel-like factor 4 (Klf4) is a zinc finger transcription factor and plays crucial roles in Xenopus embryogenesis. However, its regulation during embryogenesis is still unclear. Here, we report that Tcf7l1, a key downstream transducer of the Wnt signaling pathway, could promote Klf4 transcription ...more>>
J Biomed Res 2018;32(3):215-221.   doi:10.7555/JBR.32.20170056
In silico prediction of monovalent and chimeric tetravalent vaccines for prevention and treatment of dengue fever
Vijayakumar Subramaniyan,Ramesh Venkatachalam,Prabhu Srinivasan,Manogar Palani
Reverse vaccinology method was used to predict the monovalent peptide vaccine candidate to produce antibodies for therapeutic purpose and to predict tetravalent vaccine candidate to act as a common vaccine to cover all the dengue virus serotypes. Envelope (E)-proteins of DENV-1-4 serotypes were used...more>>
J Biomed Res 2018;32(3):222-236.   doi:10.7555/JBR.31.20160109
Molecular characterization of antimicrobial multi-drug resistance in non-typhoidal Salmonellae from chicken and clam in Mangalore, India
Yemisi Olukemi Adesiji,Santhosh Kogaluru Shivakumaraswamy,Vijaya Kumar Deekshit,Girisha Shivani Kallappa,Indrani Karunasagar
Salmonella enterica has been documented as one of the leading causes of salmonellosis throughout the world and is most commonly associated with the consumption of contaminated food products. Thus, this research was aimed at studying the antimicrobial susceptibility pattern and detection of quinolone...more>>
J Biomed Res 2018;32(3):237-244.   doi:10.7555/JBR.31.20160094
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